Case report of a neonate with ocular toxoplasmosis due to congenital infection: estimation of the percentage of ocular toxoplasmosis in Greece caused by congenital or acquired infection
نویسندگان
چکیده
We report a case of a newborn male child with congenital toxoplasmosis. During pregnancy seroconversion occurred and positive titers of antitoxoplasmic antibodies (immunoglobulin M and G) were found in the mother, in the third trimester. She received treatment with spiramycin. After birth, the neonate presented with chorioretinitis and intracranial calcifications. The neonate received treatment with pyrimethamine, sulfadiazine, and leucovorin for 1 year. In addition to using a previously described method, we report for the first time in Greece an estimation regarding the percentage of ocular toxoplasmosis caused by congenital or acquired infection. We estimate that ocular toxoplasmosis in Greece is caused in 7% of the cases by congenital infection, and in 93% of the cases by acquired infection.
منابع مشابه
Determination of the frequency and response to treatment of ocular lesions in children with various types of intrauterine infections (cytomegalovirus and toxoplasmosis): brief report
Background: Intrauterine infections (TORCH) lead to the involvement of various organs of the body of the fetus, including the eye. The aim of this study was to determine the frequency and clinical response of eye lesions to specific drugs, in infants with confirmed TORCH induced ocular lesions. Methods: This historical cohort study from 2011 to 2017, had done in Pediatrics and Ophthalmology De...
متن کاملبررسی سرواپیدمیولوژی عفونت توکسوپلاسمادر زنان باردار شهر یزد سال 1391
Introduction: Toxoplasmosis, caused by a protozoan called" Toxoplasma gondii", is one of the most common parasitic infections in humans and animals throughout the world. Toxoplasma infection in pregnant women, especially at the first trimester of pregnancy, may lead to miscarriage or birth complications in the nervous system and ocular complications. Conducting such studies can provide practica...
متن کاملIs ocular toxoplasmosis caused by prenatal or postnatal infection?
Ocular toxoplasmosis is commonly attributed to prenatally acquired (congenital) infection unless there is clear evidence that infection was acquired postnatally. We challenge this view by comparing the risks of ocular disease caused by prenatal and postnatal toxoplasmosis. As the history, clinical appearances, and serological findings associated with the two aetiologies are frequently indisting...
متن کاملUso do CD25 como um marcador imuno-histoquímico de toxoplasmose ocular adquirida
INTRODUCTION T oxoplasmosis is caused by the intracellular protozoan Toxoplasma gondii , that infects up to a third of the world’s population. Infections may be acquired congenitally or through the ingestion or handling of undercooked or raw infected meat, contaminated vegetables or water. The disease is asymptomatic in many immunocompetent hosts, however ocular lesions may be present in up to ...
متن کاملبررسی بروز توکسوپلاسموز در نوزادان و عوارض آن
Introduction: Congenital toxoplasmosis is caused by acute toxoplasma gondii infection of mother during pregnancy, which may lead to such serious complications as stillbirth, ophthalmologic and neurologic disorders. The aim of this study was to determine the incidence of toxoplasmosis in pregnant women and their neonates, and disease complications. Methods: In this prospective cohort study, blo...
متن کامل